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Save the date for flagship STAT Summit! October 16-17, 2024 in Boston, MA
2024 STAT Breakthrough Summit West May 16th in San Francisco & Virtual

Medicine’s future, now

About Breakthrough West

Thank you for joining us at 2024 Breakthrough West

The 2024 Breakthrough West Summit peered into the mists of the next two decades, looking at advances in DNA sequencing, the state of the wearables revolution, and the potential of artificial intelligence to change the way drugs are discovered — and how medicine is practiced.

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Speakers

Thank you to the speakers of 2024 Breakthrough West!

Elisabeth Bik, Ph.D.

Elisabeth Bik, Ph.D.

Science Integrity Consultant

Peter Lee, Ph.D.

Peter Lee, Ph.D.

President, Microsoft Research

Andy Coravos

Andy Coravos

Managing Director, HumanFirst, acquired by ICON

Colin Murdoch

Colin Murdoch

President of Isomorphic Labs & Chief Business Officer, Google DeepMind

Kimberly Powell

Kimberly Powell

Vice President of Healthcare, NVIDIA

Sholto David, Ph.D.

Sholto David, Ph.D.

Former Analytical Scientist

Ida Sim, M.D., Ph.D.

Ida Sim, M.D., Ph.D.

Professor and Chief Research Informatics Officer, UCSF

Bob Kocher, M.D.

Bob Kocher, M.D.

Partner, Venrock

Gilad Almogy, Ph.D.

Gilad Almogy, Ph.D.

CEO and Co-Founder, Ultima Genomics

Ayesha Appa, M.D.

Ayesha Appa, M.D.

Addiction Medicine & Infectious Diseases Physician; Assistant Professor of Medicine, UCSF

Jared Baeten, M.D., Ph.D.

Sponsor Speaker

Jared Baeten, M.D., Ph.D.

Vice President, HIV Clinical Development, Gilead Sciences

Robert Blum

Robert Blum

President & CEO, Cytokinetics

Richard Bonneau, Ph.D.

Sponsor Speaker

Richard Bonneau, Ph.D.

VP Machine Learning for Drug Discovery, Genentech

Braunz Courtney

Braunz Courtney

Executive Director, HIV Education and Prevention Project of Alameda County (HEPPAC)

Patricia Brennan

Sponsor Speaker

Patricia Brennan

Vice President of Science Technology, Chan Zuckerberg Initiative

Melissa Hanna, J.D.

Melissa Hanna, J.D.

Co-Founder & CEO, Mahmee

Patrick Hsu, Ph.D.

Patrick Hsu, Ph.D.

Co-Founder and Core Investigator of the Arc Institute and assistant Ppofessor of Bioengineering at the University of California, Berkeley

Keith Humphreys, Ph.D.

Keith Humphreys, Ph.D.

Esther Ting Memorial Professor of Psychiatry and Behavioral Sciences, Stanford University

Theofanis Karaletsos

Sponsor Speaker

Theofanis Karaletsos

Head of AI for Science, Chan Zuckerberg Initiative

David Kim, M.D.

David Kim, M.D.

Executive Vice President, Clinical Institutes MemorialCare Health System and Chief Executive Officer, MemorialCare Medical Foundation

Daphne Koller, Ph.D.

Daphne Koller, Ph.D.

CEO and Founder, insitro

Derek Lowe, Ph.D.

Derek Lowe, Ph.D.

Director, Discovery Sciences, Novartis; Author, “In the Pipeline”

Akira Matsuno

Akira Matsuno

President, Chief Financial Officer, and Co-Founder, Tune

Vijay Pande, Ph.D.

Vijay Pande, Ph.D.

General Partner, Andreessen Horowitz

Dina Radenkovic, MBBS

Dina Radenkovic, MBBS

CEO and Co-Founder, Gameto

Shiv Rao, M.D.

Shiv Rao, M.D.

CEO & Founder, Abridge

Mike Rea

Mike Rea

CEO, IDEA Pharma

Kimberly Seals Allers

Kimberly Seals Allers

Founder, IRTH

Simmone Taitt

Simmone Taitt

Founder & CEO, Poppy Seed Health

Erica Taylor, Ph.D.

Sponsor Speaker

Erica Taylor, Ph.D.

Vice President, Chief Marketing Officer, Genentech

Pierre Theodore, M.D.

Sponsor Speaker

Pierre Theodore, M.D.

Head, Patient Impact and Health Equity, Genentech

Mario Aguilar

Moderator

Mario Aguilar

Health Tech Correspondent, STAT

Rick Berke

Moderator

Rick Berke

Co-Founder and Executive Editor, STAT

Allison DeAngelis

Moderator

Allison DeAngelis

Biotech Startups and Venture Capital Reporter, STAT

Adam Feuerstein

Moderator

Adam Feuerstein

Senior Writer, Biotech, STAT

Matthew Herper

Moderator

Matthew Herper

Senior Writer, Medicine; Editorial Director of Events, STAT

Lizzy Lawrence

Moderator

Lizzy Lawrence

Medical Devices Reporter, STAT

Katherine MacPhail

Moderator

Katherine MacPhail

Programmer, Editorial Events, STAT

Usha Lee McFarling

Moderator

Usha Lee McFarling

National Science Correspondent, STAT

Mohana Ravindranath

Moderator

Mohana Ravindranath

Bay Area Correspondent, STAT

Casey Ross

Moderator

Casey Ross

National Health Technology Correspondent, STAT

Nicholas St. Fleur

Moderator

Nicholas St. Fleur

General Assignment Reporter; Associate Editorial Director of Events, STAT

Jonathan Wosen, Ph.D.

Moderator

Jonathan Wosen, Ph.D.

West Coast Biotech & Life Sciences Reporter, STAT

AGENDA

Explore the sessions of 2024 Breakthrough West

May 16, 2024

7:30 a.m.

Arrival & Registration

Networking breakfast for all attendees.

8:45 a.m.

Welcome from STAT

10 min

8:55 a.m.
Sponsor Session

Opening Remarks

5 min
Erica Taylor, Ph.D., vice president, chief marketing officer, Genentech

9:00 a.m.

Will the Doctor GPT You Now?

20 min
Peter Lee, Ph.D., president, Microsoft Research Nicholas St. Fleur, general assignment reporter, associate editorial director of events, STAT (moderator)

Microsoft has emerged as a leading player in generative AI, including in health care. The first big foray is in note-taking. But how else could large language models help doctors do their jobs?

9:20 a.m.

NVIDIA Takes On One of the World’s Biggest Challenges: Inventing Drugs

20 min
Kimberly Powell, vice president of Healthcare, NVIDIA Casey Ross, national health technology correspondent, STAT (moderator)

Few human endeavors are as beset by expensive failure as the quest to develop drugs – and new technologies rarely move the needle. Will generative AI be different? Hear the case for “yes.”

9:40 a.m.
Sponsor Session

How AI Can Help Us Make Better Medicines

10 min
Richard Bonneau, Ph.D., VP machine learning for drug discovery, Genentech Matthew Herper, senior writer, medicine; editorial director of events, STAT (moderator)

We’re in an unprecedented time where computational methods, especially from AI/Machine Learning, are becoming just as essential as biology and chemistry to the future of medicines. Genentech is pioneering a strategy called the “Lab in a Loop” – an iterative cycle of data, computation, experimentation, and discovery – that is accelerating and improving drug discovery and development.

9:50 a.m.

Going Deeper into Using Generative AI to Design Drugs

20 min
Colin Murdoch, president, Isomorphic Labs & chief business officer, Google DeepMind Casey Ross, national health technology correspondent, STAT (moderator)

In developing AlphaFold, Google DeepMind solved one of the enduring grand challenges of computational biology — predicting the 3D structure of proteins from their amino acid sequences. The next test is turning that fundamental breakthrough into a business that can help pharma develop new medicines. Here’s a closer look at how it’s going.

10:10 a.m.

Grasping the Genome’s Grammar

15 min
Patrick Hsu, Ph.D., co-founder and Core Investigator of the Arc Institute; assistant professor of bioengineering at the University of California, Berkeley Matthew Herper, senior writer, medicine; editorial director of events, STAT (moderator)

The ARC Institute represents a new approach to a research institute, bridging academia and industry. Hear how some of the results there could change the way that researchers understand and manipulate DNA.

10:25 a.m.

Ranking Drug Companies on Innovation and Invention

5 min
Mike Rea, CEO, IDEA Pharma

IDEA Pharma unveils the 13th annual edition of its ranking of the companies that do the best jobs creating medicines and bringing them to market.

10:30 a.m.

COFFEE BREAK

30 min

11:00 a.m.

The Opioid Crisis: Harm Reduction vs. Harm

30 min
Ayesha Appa, M.D., addiction medicine & infectious diseases physician; assistant professor of medicine, UCSF Braunz Courtney, executive director, HIV Education and Prevention Project of Alameda County (HEPPAC) Keith Humphreys, Ph.D., Esther Ting Memorial Professor of Psychiatry and Behavioral Sciences, Stanford University Lev Facher, addiction reporter, STAT (moderator)

In a bid to decrease opioid deaths, the U.S. has increasingly embraced harm reduction tactics like syringe exchange and fentanyl test strips. But the approach is now facing major resistance even in historically progressive cities. If harm reduction works, why is it so unpopular? We’ll look at the data, the politics, and the response to the drug crisis in San Francisco and across the country.

11:30 a.m.

The Long View on Health Care: The Change Hack, AI Bets & Health Tech’s Future

20 min
Bob Kocher, M.D., partner, Venrock Mohana Ravindranath, Bay Area correspondent, STAT (moderator)

A key architect of the Affordable Care Act is now one of tech’s most influential investors. Hear Bob Kocher reflect on this year’s biggest news: the Change Healthcare attack, the explosion of generative AI startups vying for investor dollars, and the future of digital health – and see what he thinks will be coming up next for health care startups.

11:50 a.m.
Sponsor Session

How Artificial Intelligence is Powering the Future of Biomedical Science

10 min
Patricia Brennan, vice president of science technology, Chan Zuckerberg Initiative Theofanis Karaletsos, head of AI for science, Chan Zuckerberg Initiative Nicholas St. Fleur, general assignment reporter, associate editorial director of events, STAT (moderator)

Artificial intelligence (AI) has enormous potential to accelerate the pace of science and medicine. The Chan Zuckerberg Initiative (CZI) is building and funding one of the largest AI computing systems for nonprofit life science research in the world to enable virtual cell models that are capable of predicting the behavior of healthy and diseased cells. Explore how AI-powered virtual cell models will help scientists unlock the molecular underpinnings of human health and disease.

12:00 p.m.

Science’s New Watchdogs

30 min
Elisabeth Bik, Ph.D., science integrity consultant Sholto David, Ph.D., former analytical scientist Jonathan Wosen, PhD., west coast biotech & life sciences reporter, STAT (moderator)

The discovery of reused or altered images in scientific papers is shining a bright and uncomfortable spotlight on the research world, leading to a string of retracted papers and even some surprising resignations. Meet two key figures in this major scientific moment for a tough discussion about what is coming next.

12:30 p.m.

LUNCH

85 min

2:00 p.m.

Can AI Fix Medical Documentation?

15 min
David Kim, M.D., executive vice president, Clinical Institutes MemorialCare Health System and chief executive officer, MemorialCare Medical Foundation Shiv Rao, M.D., CEO & founder, Abridge Katherine MacPhail, programmer, editorial events, STAT (moderator)

One of the nearest benefits from artificial intelligence in medicine could be keeping better track of conversations between patients and doctors – without forcing the doctor to hunch over the electronic medical record. See this play out live.

2:15 p.m.

The STAT Startup Panel

35 min
Gilad Almogy, Ph.D., CEO and co-founder, Ultima Genomics Akira Matsuno, president, chief financial officer, and co-founder, Tune Therapeutics Dina Radenkovic, MBBS, CEO and Co-Founder, Gameto Allison DeAngelis, biotech startups and venture capital reporter, STAT (moderator)

Come hear from three of the most interesting new companies in the health care universe – bridging drug development, health tech, and more. Find out the next targets for medical entrepreneurs.

2:50 p.m.
Sponsor Session

Ending the HIV Epidemic – Our Path Toward a Cure

10 min
Jared Baeten, M.D., Ph.D., vice president HIV clinical development, Gilead Sciences Rick Berke, co-founder and executive editor, STAT (moderator)

For 35 years, Gilead has been a leading innovator in the field of HIV, driving advances in treatment, prevention and cure research. From the first single-tablet regimen to treat HIV to the first antiretroviral for pre-exposure prophylaxis (PrEP) to help reduce new HIV infections and now to the first long-acting injectable HIV treatment medication administered twice-yearly – our advances in medical research have helped to transform HIV into a treatable, preventable, chronic condition for millions of people. As we forge ahead on the path to a cure, here’s how we aim to address the most pressing needs of the day and keep people impacted by HIV at the center of all that we do.

3:00 p.m.

Can Health Tech Combat Black Maternal Mortality?

30 min
Melissa Hanna, J.D., co-founder & CEO, Mahmee Kimberly Seals Allers, founder, Irth App Simmone Taitt, founder & CEO, Poppy Seed Health Usha Lee McFarling, national science correspondent, STAT (moderator)

Black maternal mortality is nearly triple the rate for white women. These startups are trying to reduce this awful disparity, helping pregnant people avoid subpar hospitals, connect with doulas, and track health metrics.

3:30 p.m.

Can Wearables Still Upend Medicine?

30 min
Ida Sim, M.D., Ph.D., professor and chief research informatics officer, UCSF Andy Coravos, managing director, HumanFirst, acquired by ICON Mario Aguilar, health tech correspondent, STAT (moderator)

It’s been almost a decade since the Apple Watch started to catalyze a new interest in using wearables for medical diagnosis. But hype has met reality all too often. What is next, and what role should industry and academia play in changing how our devices monitor us?

4:00 p.m.

COFFEE BREAK

30 min

4:30 p.m.

A Biotech With Heart

25 min
Robert Blum, president & CEO, Cytokinetics Adam Feuerstein, senior writer, biotech, STAT (moderator)

The story of Cytokinetics is one of perseverance, stubbornness, and setbacks overcome. Founded in 1997 to exploit emerging science in muscle biology, the company is finally on the cusp of its first drug approval for aficamten, a treatment for an inherited form of heart disease. Retrace the bumpy road to this triumphant moment and look toward the future with the company’s long-time CEO.

4:55 p.m.

Setting Expectations for AI In Drug Development

40 min
Daphne Koller, Ph.D., CEO and founder, insitro Derek Lowe, Ph.D. director, discovery sciences, Novartis; author, “In the Pipeline” Vijay Pande, Ph.D., general partner, Andreessen Horowitz Matthew Herper, senior writer, medicine; editorial director of events, STAT (moderator)

The advent of generative AI means hopes for advances in drug development have never been higher. What is realistic? What is not?

5:35 p.m.
Sponsor Session

Closing Remarks

5 min
Pierre Theodore, M.D., Head, Patient Impact and Health Equity, Genentech

5:40 p.m.

Closing from STAT

5 min

5:45 p.m.

Networking Reception

90 min

Open to all summit attendees.

Location

The meeting of the minds in San Francisco

The 2024 STAT Breakthrough Summit West took place at the Commonwealth Club at 110 The Embarcadero, San Francisco, CA with virtual programming available on our cutting edge virtual event platform.

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