Harvard scientists unveil the most detailed map of the brain ever: ‘It’s an alien world inside your own head’

About 10 years ago, a small piece of human brain arrived in the lab of Dr. Jeffrey Lichtman at Harvard. It came directly from an operating room of a nearby hospital, where it was excised from an epilepsy patient undergoing a procedure to reduce her seizures.

In the years that followed, Lichtman’s team methodically reconstructed the byzantine wiring patterns of the brain by feeding the 1-cubic-millimeter sample into a $6 million device that sliced it into impossibly-thin slivers. Then, using images of those slivers taken by electron microscopy, they painstakingly recreated the intricate latticework connecting individual cells to one another.

The result is the most-detailed digital map, or “connectome,” of the human brain ever created.

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